It depends. It depends on which state you are homeschooling in, and it depends on what colleges and universities you are applying to.
In the state of Texas, the homeschooling laws are such that the parent is in charge of the student's transcript.
In the state of California, students' high school coursework has to meet the UC-Ag curriculum approved standard, for example (we are approved by UC-Ag, by the way).
For parents and students who want 100% certainty and peace of mind, we recommend the North Atlantic Regional High School (NARHS) accreditation process. You can visit their website here.
If you have any further questions, please email us at email@example.com.